C-Myb(+) Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

Although classified as hematopoietic cells, tissue- resident macrophages (MFs) arise from embryonic precursors that seed the tissues prior to birth to generate a self-renewing population, which is maintained independently of adult hematopoiesis. Here we reveal the identity of these embryonic precurs...

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Veröffentlicht in:Immunity
Hauptverfasser: Hoeffel, Guillaume, Chen, Jinmiao, Lavin, Yonit, Low, Donovan, Almeida, Francisca F., See, Peter, Beaudin, Anna E., Lum, Josephine, Low, Ivy, Forsberg, E. Camilla, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Ng, Lai Guan, Chan, Jerry K.Y., Greter, Melanie, Becher, Burkhard, Samokhvalov, Igor M., Merad, Miriam, Ginhoux, Florent
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545768/
https://ncbi.nlm.nih.gov/pubmed/25902481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.011
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