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Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells

Gefitinib and erlotinib are anticancer agents, which inhibit epidermal growth factor receptor (EGFR) tyrosine kinase. Interstitial lung disease (ILD) occurs in patients with non-small cell lung cancer receiving EGFR inhibitors. In the present study, we examined whether gefitinib- and erlotinib-induc...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Koyama, Satoshi, Omura, Tomohiro, Yonezawa, Atsushi, Imai, Satoshi, Nakagawa, Shunsaku, Nakagawa, Takayuki, Yano, Ikuko, Matsubara, Kazuo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545731/
https://ncbi.nlm.nih.gov/pubmed/26288223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136176
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