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Tau Pathology Spread in PS19 Tau Transgenic Mice Following Locus Coeruleus (LC) Injections of Synthetic Tau Fibrils is Determined by the LC’s Afferent and Efferent Connections

Filamentous tau inclusions are hallmarks of Alzheimer’s disease (AD) and other neurodegenerative tauopathies. An increasing number of studies implicate the cell-to-cell propagation of tau pathology in the progression of tauopathies. We recently showed [25] that inoculation of preformed synthetic tau...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol
Main Authors: Iba, Michiyo, McBride, Jennifer D., Guo, Jing L., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545685/
https://ncbi.nlm.nih.gov/pubmed/26150341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1458-4
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