ロード中...
MK1775, A Selective Wee1 Inhibitor, Shows Single-Agent Antitumor Activity Against Sarcoma Cells
Wee1 is a critical component of the G2/M cell cycle checkpoint control and mediates cell cycle arrest by regulating the phosphorylation of CDC2. Inhibition of Wee1 by a selective small molecule inhibitor MK1775 can abrogate G2/M checkpoint resulting in premature mitotic entry and cell death. MK1775...
保存先:
| 出版年: | Mol Cancer Ther |
|---|---|
| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545500/ https://ncbi.nlm.nih.gov/pubmed/22084170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0529 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|