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WEE1 inhibition by MK1775 as a single-agent therapy inhibits ovarian cancer viability
Wee1-like protein kinase (WEE1) physiologically serves a key function in maintaining the integrity of the cell genome through mediating the activation of cyclin-dependent kinase (CDK)1 and CDK2. Increased expression of WEE1 has been associated with the poor prognosis of patients with ovarian cancer....
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588002/ https://ncbi.nlm.nih.gov/pubmed/28927115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6584 |
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