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Overlapping requirements for Tet2 and Tet3 in normal development and hematopoietic stem cell emergence

The Tet family of methylcytosine dioxygenases (Tet1, Tet2 and Tet3) convert 5-methylcytosine to 5-hydroxymethylcytosine. To date, functional overlap among Tet family members has not been examined systematically in the context of embryonic development. To clarify the potential for overlap among Tet e...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Li, Cheng, Lan, Yahui, Schwartz-Orbach, Lianna, Korol, Evgenia, Tahiliani, Mamta, Evans, Todd, Goll, Mary G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545447/
https://ncbi.nlm.nih.gov/pubmed/26257178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.025
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