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TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis

Ten-eleven translocation (Tet) enzymes (Tet1/2/3) mediate 5-methylcytosine (5mC) hydroxylation, which can facilitate DNA demethylation and thereby impact gene expression. Studied mostly for how mutant isoforms impact cancer, the normal roles for Tet enzymes during organogenesis are largely unknown....

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lan, Yahui, Pan, Heng, Li, Cheng, Banks, Kelly M., Sam, Jessica, Ding, Bo, Elemento, Olivier, Goll, Mary G., Evans, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366638/
https://ncbi.nlm.nih.gov/pubmed/30650362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.076
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