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piRNA-Guided Transposon Cleavage Initiljates Zucchini-Dependent, Phased piRNA Production
PIWI-interacting RNAs (piRNAs) protect the animal germline by silencing transposons. Primary piRNAs, generated from transcripts of genomic transposon ‘junkyards’ (piRNA clusters), are amplified by the “Ping-Pong” pathway, yielding secondary piRNAs. We report that secondary piRNAs, bound to the PIWI...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545291/ https://ncbi.nlm.nih.gov/pubmed/25977554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa1264 |
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