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UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencing Machinery

piRNAs silence transposons during germline development. In Drosophila, transcripts from heterochromatic clusters are processed into primary piRNAs in the perinuclear nuage. The nuclear DEAD box protein UAP56 has been previously implicated in mRNA splicing and export, while the DEAD box protein Vasa...

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Detalhes bibliográficos
Main Authors: Zhang, Fan, Wang, Jie, Xu, Jia, Zhang, Zhao, Koppetsch, Birgit S., Schultz, Nadine, Vreven, Thom, Meignin, Carine, Davis, Ilan, Zamore, Phillip D., Weng, Zhiping, Theurkauf, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499805/
https://ncbi.nlm.nih.gov/pubmed/23141543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.040
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