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The HP1 homolog Rhino anchors a nuclear complex that suppresses piRNA precursor splicing
piRNAs guide an adaptive genome defense system that silences transposons during germline development. The Drosophila HP1 homolog Rhino is required for germline piRNA production. We show that Rhino binds specifically to the heterochromatic clusters that produce piRNA precursors, and that binding dire...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167631/ https://ncbi.nlm.nih.gov/pubmed/24906152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.030 |
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