Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion.
The rat neu gene, which encodes a receptor-like protein homologous to the epidermal growth factor receptor, is frequently activated by a point mutation altering a valine residue to a glutamic acid residue in its predicted transmembrane domain. Additional point mutations have been constructed in a no...
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| Udgivet i: | EMBO J |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03044.x |
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