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Sequence kernel association analysis of rare variant set based on the marginal regression model for binary traits

Recent sequencing efforts have focused on exploring the influence of rare variants on the complex diseases. Gene-level based tests by aggregating information across rare variants within a gene have become attractive to enrich the rare variant association signal. Among them, the sequence kernel assoc...

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Publicat a:Genet Epidemiol
Autors principals: Wu, Baolin, Pankow, James S., Guan, Weihua
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544778/
https://ncbi.nlm.nih.gov/pubmed/26282996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21913
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