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Notch: From Neural Development to Neurological Disorders

Notch is an integral membrane protein that functions as receptor for ligands such as jagged and delta that are associated with the surface of neighboring cells. Upon ligand binding, notch is proteolytically cleaved within its transmembrane domain by presenilin-1 (the enzymatic component of the γ-sec...

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Bibliografische gegevens
Gepubliceerd in:J Neurochem
Hoofdauteurs: Lathia, Justin D., Mattson, Mark P., Cheng, Aiwu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544712/
https://ncbi.nlm.nih.gov/pubmed/19094054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05715.x
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