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Notch: From Neural Development to Neurological Disorders
Notch is an integral membrane protein that functions as receptor for ligands such as jagged and delta that are associated with the surface of neighboring cells. Upon ligand binding, notch is proteolytically cleaved within its transmembrane domain by presenilin-1 (the enzymatic component of the γ-sec...
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| Udgivet i: | J Neurochem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544712/ https://ncbi.nlm.nih.gov/pubmed/19094054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05715.x |
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