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Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2(b) Haplotype

PURPOSE: Experimental autoimmune uveitis (EAU) induced in mice using the retinal antigen interphotoreceptor retinoid binding protein (IRBP) is an animal model for posterior uveitis in humans. However, EAU induced by native IRBP protein or its widely used epitope amino acid residues 1 to 20 of human...

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Gepubliceerd in:Invest Ophthalmol Vis Sci
Hoofdauteurs: Mattapallil, Mary J., Silver, Phyllis B., Cortes, Lizette M., St. Leger, Anthony J., Jittayasothorn, Yingyos, Kielczewski, Jennifer L., Moon, James J., Chan, Chi-Chao, Caspi, Rachel R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Association for Research in Vision and Ophthalmology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544201/
https://ncbi.nlm.nih.gov/pubmed/26284549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17280
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