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IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ
IL-15 is currently undergoing clinical trials to assess its efficacy for treatment of advanced cancers. The combination of IL-15 with soluble IL-15Rα generates a complex termed IL-15 superagonist (IL-15 SA) that possesses greater biological activity than IL-15 alone. IL-15 SA is considered an attrac...
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| Vydáno v: | J Immunol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
AAI
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543906/ https://ncbi.nlm.nih.gov/pubmed/26216888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500300 |
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