Mycobacterial tlyA gene product is localized to the cell-wall without signal sequence

The mycobacterial tlyA gene product, Rv1694 (MtbTlyA), has been annotated as “hemolysin” which was re-annotated as 2′-O rRNA methyl transferase. In order to function as a hemolysin, it must reach the extracellular milieu with the help of signal sequence(s) and/or transmembrane segment(s). However, t...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Kumar, Santosh, Mittal, Ekansh, Deore, Sapna, Kumar, Anil, Rahman, Aejazur, Krishnasastry, Musti V.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543871/
https://ncbi.nlm.nih.gov/pubmed/26347855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2015.00060
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