Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis*

Mycobacterium tuberculosis, the causative agent of tuberculosis, is an ancient pathogen and a major cause of death worldwide. Although various virulence factors of M. tuberculosis have been identified, its pathogenesis remains incompletely understood. TlyA is a virulence factor in several bacterial...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rahman, Md. Aejazur, Sobia, Parveen, Dwivedi, Ved Prakash, Bhawsar, Aakansha, Singh, Dhiraj Kumar, Sharma, Pawan, Moodley, Prashini, Van Kaer, Luc, Bishai, William R, Das, Gobardhan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505508/
https://ncbi.nlm.nih.gov/pubmed/25847237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.653600
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