Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production versus consumption, may be involved in the pathogenesis of different diseases. The only known enzymes solely dedicated to ROS generation are nicotinamide adenine dinucleotide phosphate (NADPH) oxidases with their c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antioxid Redox Signal
Egile Nagusiak: Altenhöfer, Sebastian, Radermacher, Kim A., Kleikers, Pamela W.M., Wingler, Kirstin, Schmidt, Harald H.H.W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2015
Gaiak:
Forum Review Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543484/
https://ncbi.nlm.nih.gov/pubmed/24383718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5814
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