Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production versus consumption, may be involved in the pathogenesis of different diseases. The only known enzymes solely dedicated to ROS generation are nicotinamide adenine dinucleotide phosphate (NADPH) oxidases with their c...

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Detaylı Bibliyografya
Yayımlandı:Antioxid Redox Signal
Asıl Yazarlar: Altenhöfer, Sebastian, Radermacher, Kim A., Kleikers, Pamela W.M., Wingler, Kirstin, Schmidt, Harald H.H.W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2015
Konular:
Forum Review Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543484/
https://ncbi.nlm.nih.gov/pubmed/24383718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5814
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