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Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers
PURPOSE: The role of CHEK2 in DNA repair by homologous recombination suggests that CHEK2-associated breast cancer (BC) patients might be more sensitive to chemotherapy inducing double-strand DNA breaks, but results hereon are lacking. We compared the sensitivity to first-line chemotherapy and endocr...
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| Pubblicato in: | J Cancer Res Clin Oncol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543421/ https://ncbi.nlm.nih.gov/pubmed/25958056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-015-1981-7 |
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