Antisense oligonucleotide-directed cleavage of mRNA in Xenopus oocytes and eggs.

We have investigated the effect of specific antisense oligonucleotides on both exogenous and endogenous mRNAs in Xenopus oocytes and eggs. Injection of 19- or 20-mers complementary to 70-kd heat shock protein, histone H4 and vegetally localized Veg 1 coding sequences causes rapid cleavage and degrad...

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Pubblicato in:	EMBO J
Autori principali:	Shuttleworth, J, Colman, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2452730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02830.x
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