Antisense oligonucleotide-directed cleavage of mRNA in Xenopus oocytes and eggs.

We have investigated the effect of specific antisense oligonucleotides on both exogenous and endogenous mRNAs in Xenopus oocytes and eggs. Injection of 19- or 20-mers complementary to 70-kd heat shock protein, histone H4 and vegetally localized Veg 1 coding sequences causes rapid cleavage and degrad...

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發表在:	EMBO J
Principais autores:	Shuttleworth, J, Colman, A
格式:	Artigo
語言:	Inglês
出版:	Nature Publishing Group 1988
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2452730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02830.x
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