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The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.

We have introduced into murine erythroleukaemia (MEL) cells several series of deletion mutants of hybrid genes between the human beta-globin gene and the murine H-2Kb gene. S1 nuclease and transcriptional run-off analysis showed that the human beta-globin gene contains at least three globin specific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Antoniou, M, deBoer, E, Habets, G, Grosveld, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC454330/
https://ncbi.nlm.nih.gov/pubmed/2835225
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