The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.
We have introduced into murine erythroleukaemia (MEL) cells several series of deletion mutants of hybrid genes between the human beta-globin gene and the murine H-2Kb gene. S1 nuclease and transcriptional run-off analysis showed that the human beta-globin gene contains at least three globin specific...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2835225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02824.x |
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