Localization of the putative precursor of Alzheimer's disease-specific amyloid at nuclear envelopes of adult human muscle.

Cloning and sequence analysis revealed the putative amyloid A4 precursor (pre-A4) of Alzheimer's disease to have characteristics of a membrane-spanning glycoprotein. In addition to brain, pre-A4 mRNA was found in adult human muscle and other tissues. We demonstrate by in situ hybridization that...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Zimmermann, K, Herget, T, Salbaum, J M, Schubert, W, Hilbich, C, Cramer, M, Masters, C L, Multhaup, G, Kang, J, Lemaire, H G
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1988
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2896589/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02822.x
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