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Detection of miRNA Targets in High-throughput Using the 3'LIFE Assay

Luminescent Identification of Functional Elements in 3’UTRs (3’LIFE) allows the rapid identification of targets of specific miRNAs within an array of hundreds of queried 3’UTRs. Target identification is based on the dual-luciferase assay, which detects binding at the mRNA level by measuring translat...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Autores principales: Wolter, Justin M., Kotagama, Kasuen, Babb, Cody S., Mangone, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542967/
https://ncbi.nlm.nih.gov/pubmed/26066857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52647
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