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Impact of probe annotation on the integration of miRNA–mRNA expression profiles for miRNA target detection

MicroRNAs (miRNAs) are small non-coding RNAs that mediate gene expression at the post-transcriptional and translational levels by an imperfect binding to target mRNA 3′UTR regions. While the ab-initio computational prediction of miRNA–mRNA interactions still poses significant challenges, it is possi...

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Bibliografske podrobnosti
Main Authors: Sales, Gabriele, Coppe, Alessandro, Bicciato, Silvio, Bortoluzzi, Stefania, Romualdi, Chiara
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853140/
https://ncbi.nlm.nih.gov/pubmed/20071740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1239
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