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Detection of miRNA Targets in High-throughput Using the 3'LIFE Assay

Luminescent Identification of Functional Elements in 3’UTRs (3’LIFE) allows the rapid identification of targets of specific miRNAs within an array of hundreds of queried 3’UTRs. Target identification is based on the dual-luciferase assay, which detects binding at the mRNA level by measuring translat...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Wolter, Justin M., Kotagama, Kasuen, Babb, Cody S., Mangone, Marco
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542967/
https://ncbi.nlm.nih.gov/pubmed/26066857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52647
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