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Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics

Ionophore antibiotics were reported to selectively kill cancer stem cells and to overcome multidrug resistance, but mechanistic studies of the significance of drug transporters for treatment with these compounds are lacking. We applied chemosensitivity testing of well-characterized human cancer cell...

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Veröffentlicht in:Stem Cells Transl Med
Hauptverfasser: Boesch, Maximilian, Zeimet, Alain G., Rumpold, Holger, Gastl, Guenther, Sopper, Sieghart, Wolf, Dominik
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542876/
https://ncbi.nlm.nih.gov/pubmed/26136502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0054
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