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Ionophore Antibiotics as Cancer Stem Cell-Selective Drugs: Open Questions

Ionophore antibiotics are promising compounds with potent anticancer and anti-cancer stem cell (anti-CSC) activity. However, resistance mediated by drug transporters potentially confines their use to CSC populations that do not exhibit appreciable drug efflux capacity. Further research is required t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncologist
Hauptverfasser: Boesch, Maximilian, Sopper, Sieghart, Wolf, Dominik
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189623/
https://ncbi.nlm.nih.gov/pubmed/27486200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0159
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