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Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche

Malignancy is fuelled by distinct subsets of stem-like cells which persist under treatment and provoke drug-resistant recurrence. Eradication of these cancer stem cells has therefore become a prime objective for the development and design of novel classes of anti-cancer therapeutics with improved cl...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Boesch, Maximilian, Sopper, Sieghart, Zeimet, Alain G., Reimer, Daniel, Gastl, Guenther, Ludewig, Burkhard, Wolf, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818142/
https://ncbi.nlm.nih.gov/pubmed/27751894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2016.10.003
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