Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel

Diffuse congenital hyperinsulinism in infancy (CHI-D) arises from mutations inactivating the K(ATP) channel; however, the phenotype is difficult to explain from electrophysiology alone. Here we studied wider abnormalities in the β-cell and other pancreatic lineages. Islets were disorganized in CHI-D...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Diabetes
Egile Nagusiak: Salisbury, Rachel J., Han, Bing, Jennings, Rachel E., Berry, Andrew A., Stevens, Adam, Mohamed, Zainab, Sugden, Sarah A., De Krijger, Ronald, Cross, Sarah E., Johnson, Paul P.V., Newbould, Melanie, Cosgrove, Karen E., Hanley, Karen Piper, Banerjee, Indraneel, Dunne, Mark J., Hanley, Neil A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2015
Gaiak:
Islet Studies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542438/
https://ncbi.nlm.nih.gov/pubmed/25931474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1202
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