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Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel
Diffuse congenital hyperinsulinism in infancy (CHI-D) arises from mutations inactivating the K(ATP) channel; however, the phenotype is difficult to explain from electrophysiology alone. Here we studied wider abnormalities in the β-cell and other pancreatic lineages. Islets were disorganized in CHI-D...
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| Vydáno v: | Diabetes |
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| Hlavní autoři: | , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Diabetes Association
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542438/ https://ncbi.nlm.nih.gov/pubmed/25931474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1202 |
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