Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated pre-let-7 uridylation, inhibiting its process...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Choudhury, Nila Roy, Nowak, Jakub S., Zuo, Juan, Rappsilber, Juri, Spoel, Steven H., Michlewski, Gracjan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2014
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542301/
https://ncbi.nlm.nih.gov/pubmed/25457611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.017
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