Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated pre-let-7 uridylation, inhibiting its process...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Choudhury, Nila Roy, Nowak, Jakub S., Zuo, Juan, Rappsilber, Juri, Spoel, Steven H., Michlewski, Gracjan
Format: Artigo
Langue:Inglês
Publié: Cell Press 2014
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542301/
https://ncbi.nlm.nih.gov/pubmed/25457611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.017
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