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Survival advantage of heterozygous fV Leiden carriers in murine sepsis
BACKGROUND: The high allelic frequency of the prothrombotic Leiden polymorphism in human blood coagulation factor V (fV) has been speculated to reflect positive selection during evolution. Heterozygous Leiden carriers enrolled in the placebo arm of the PROWESS sepsis trial, and heterozygous Leiden m...
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| 出版年: | J Thromb Haemost |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542152/ https://ncbi.nlm.nih.gov/pubmed/25690763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12876 |
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