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Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor

GPR37 is an orphan G protein-coupled receptor expressed in mammalian brain, and its insoluble aggregates are found in the brain samples of juvenile Parkinson's disease patients. We have produced a Gpr37 knock-out mouse strain and identified several phenotypic features that are similar to those...

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Detalhes bibliográficos
Main Authors: Marazziti, Daniela, Golini, Elisabetta, Mandillo, Silvia, Magrelli, Armando, Witke, Walter, Matteoni, Rafaele, Tocchini-Valentini, Glauco P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC454186/
https://ncbi.nlm.nih.gov/pubmed/15218106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403661101
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