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GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs
The orphan G protein-coupled receptor 37 (GPR37) is a substrate of parkin; its insoluble aggregates accumulate in brain samples of Parkinson's disease patients. We report here that GPR37 interacts with the dopamine transporter (DAT) and modulates DAT activity. GPR37 and DAT were found colocaliz...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1887553/ https://ncbi.nlm.nih.gov/pubmed/17519329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703368104 |
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