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GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs

The orphan G protein-coupled receptor 37 (GPR37) is a substrate of parkin; its insoluble aggregates accumulate in brain samples of Parkinson's disease patients. We report here that GPR37 interacts with the dopamine transporter (DAT) and modulates DAT activity. GPR37 and DAT were found colocaliz...

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מידע ביבליוגרפי
Main Authors: Marazziti, Daniela, Mandillo, Silvia, Di Pietro, Chiara, Golini, Elisabetta, Matteoni, Rafaele, Tocchini-Valentini, Glauco P.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887553/
https://ncbi.nlm.nih.gov/pubmed/17519329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703368104
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