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Resistance in the Ribosome: RUNX1, pre-LSCs, and HSPCs
Therapeutic targeting of pre-leukemic stem cells (pre-LSCs) may be a viable strategy to eradicate residual disease and prevent leukemia relapse. Now in Cell Stem Cell, Cai et al. (2015) show that loss-of-function mutations in RUNX1 reduce ribosome biogenesis and provide pre-LSCs a selective advantag...
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Publicado no: | Cell Stem Cell |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4541802/ https://ncbi.nlm.nih.gov/pubmed/26253196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.07.012 |
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