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Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells

Successful myeloid differentiation depends on the expression of a series of miRNAs. Thus, it is hardly surprising that miRNAs are globally repressed in AML, a disease mainly characterized by a block in cellular myeloid differentiation. Studies investigating the mechanisms for low miRNA expression in...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Wampfler, Julian, Federzoni, Elena A., Torbett, Bruce E., Fey, Martin F., Tschan, Mario P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541502/
https://ncbi.nlm.nih.gov/pubmed/25990244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1AB0514-258R
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