BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation

BACKGROUND: Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP BIRC6 is associated with unfavorable clinical features and negatively impacts relapse-free survival in childhood acute myel...

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Bibliographic Details
Main Authors: Schläfli, Anna M, Torbett, Bruce E, Fey, Martin F, Tschan, Mario P
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514096/
https://ncbi.nlm.nih.gov/pubmed/23211188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-25
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