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Versatility of Particulate Carriers: Development of Pharmacodynamically Optimized Drug-Loaded Microparticles for Treatment of Peritoneal Cancer

Intraperitoneal (IP) chemotherapy confers significant survival benefits in cancer patients. However, several problems, including local toxicity and ineffectiveness against bulky tumors, have prohibited it from becoming a standard-of-care. We have developed drug-loaded, tumor-penetrating microparticl...

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Dettagli Bibliografici
Pubblicato in:AAPS J
Autori principali: Au, Jessie L.-S., Lu, Ze, Wientjes, M. Guillaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540721/
https://ncbi.nlm.nih.gov/pubmed/26089090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9785-x
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