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Versatility of Particulate Carriers: Development of Pharmacodynamically Optimized Drug-Loaded Microparticles for Treatment of Peritoneal Cancer

Intraperitoneal (IP) chemotherapy confers significant survival benefits in cancer patients. However, several problems, including local toxicity and ineffectiveness against bulky tumors, have prohibited it from becoming a standard-of-care. We have developed drug-loaded, tumor-penetrating microparticl...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Au, Jessie L.-S., Lu, Ze, Wientjes, M. Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540721/
https://ncbi.nlm.nih.gov/pubmed/26089090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9785-x
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