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Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences
Genome-scale methods have identified thousands of candidate cis-regulatory elements, but methods to directly assay the regulatory function of these elements on a comparably large scale have not been available. The inability to directly test and perturb the regulatory activity of large numbers of DNA...
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| Publicado en: | Genomics |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540672/ https://ncbi.nlm.nih.gov/pubmed/26072432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.06.003 |
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