Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling

Recently we have demonstrated the importance of RBPjk-dependent Notch signaling in the regulation of mesenchymal stem cell (MSC) differentiation during skeletogenesis both in vivo and in vitro. Here we further performed RBPJK loss-of-function experiments to demonstrate for the first time that RBPJK...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shang, Xifu, Luo, Zhengliang, Wang, Xudong, Jaeblon, Todd, Marymont, John V., Dong, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540435/
https://ncbi.nlm.nih.gov/pubmed/26285013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135971
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