Alcohol Dehydrogenase-1B (rs1229984) and Aldehyde Dehydrogenase-2 (rs671) Genotypes Are Strong Determinants of the Serum Triglyceride and Cholesterol Levels of Japanese Alcoholic Men

BACKGROUND: Elevated serum triglyceride (TG) and high-density-lipoprotein cholesterol (HDL-C) levels are common in drinkers. The fast-metabolizing alcohol dehydrogenase-1B encoded by the ADH1B*2 allele (vs. ADH1B*1/*1 genotype) and inactive aldehyde dehydrogenase-2 encoded by the ALDH2*2 allele (vs....

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Veröffentlicht in:PLoS One
Hauptverfasser: Yokoyama, Akira, Yokoyama, Tetsuji, Matsui, Toshifumi, Mizukami, Takeshi, Kimura, Mitsuru, Matsushita, Sachio, Higuchi, Susumu, Maruyama, Katsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540432/
https://ncbi.nlm.nih.gov/pubmed/26284938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133460
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