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Combinations of alcohol-induced flushing with genetic polymorphisms of alcohol and aldehyde dehydrogenases and the risk of alcohol dependence in Japanese men and women

OBJECTIVE: The risk of alcohol dependence (AD) in Japanese men and women was evaluated according to combinations of alcohol flushing and aldehyde dehydrogenase-2 (ALDH2, rs671) and alcohol dehydrogenase-1B (ADH1B, rs1229984) genotypes, all of which are known to determine AD susceptibility in Asians....

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Bibliographic Details
Published in:PLoS One
Main Authors: Yokoyama, Akira, Yokoyama, Tetsuji, Kimura, Mitsuru, Matsushita, Sachio, Yokoyama, Masako
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312924/
https://ncbi.nlm.nih.gov/pubmed/34310648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0255276
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