Recovery from anemia and leukocytopenia after abstinence in Japanese alcoholic men and their genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2

BACKGROUND: The combination of the fast-metabolizing alcohol dehydrogenase-1B (ADH1B*2 allele) and inactive heterozygous aldehyde dehydrogenase-2 (ALDH2*1/*2) increases susceptibility to macrocytic anemia and leukocytopenia in alcoholics due to severe acetaldehydemia. More than half of Japanese drin...

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Bibliographic Details
Published in:Jpn J Clin Oncol
Main Authors: Yokoyama, Akira, Brooks, Philip J., Yokoyama, Tetsuji, Mizukami, Takeshi, Shiba, Shunsuke, Nakamoto, Nobuhiro, Maruyama, Katsuya
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283107/
https://ncbi.nlm.nih.gov/pubmed/28158658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jjco/hyw208
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