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Adhesion-Induced Unclasping of Cytoplasmic Tails of Integrin α(IIb)β(3)(,)

Integrin α(IIb)β(3) plays a pivotal role in hemostasis and thrombosis by mediating adhesive interactions of platelets. Binding of α(IIb)β(3) to its physiological ligands, immobilized fibrinogen and fibrin, induces outside-in signaling in platelets, leading to their adhesion and spreading even withou...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Podolnikova, Nataly P., O’Toole, Timothy E., Haas, Thomas A., Lam, Stephen C.-T., Fox, Joan E. B., Ugarova, Tatiana P.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540355/
https://ncbi.nlm.nih.gov/pubmed/19117493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801751s
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