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Adhesion-Induced Unclasping of Cytoplasmic Tails of Integrin α(IIb)β(3)(,)
Integrin α(IIb)β(3) plays a pivotal role in hemostasis and thrombosis by mediating adhesive interactions of platelets. Binding of α(IIb)β(3) to its physiological ligands, immobilized fibrinogen and fibrin, induces outside-in signaling in platelets, leading to their adhesion and spreading even withou...
Tallennettuna:
| Julkaisussa: | Biochemistry |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540355/ https://ncbi.nlm.nih.gov/pubmed/19117493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801751s |
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